The Practical of Healing & Repair
Healing of inflammation often involves in growth of capillaries and fibroblasts. This forms granulation tissue. Here, an acute myocardial infarction is seen healing. There are numerous capillaries, and collagen is being laid down to form a scar. Non-infracted myocardium is present at the far left.At high magnification, granulation tissue has capillaries, fibroblasts, and a variable amount of inflammatory cells (mostly mononuclear)
Recently formed granulation tissue ( capillaries, fibroblasts & collagen fibers) at site of incised wound, the overlying epidermis heals by regeneration.
This is a healing biopsy site on the skin seen a week following the excision, The skin surface has re-epithelialized, and below this is granulation tissue with small capillaries and fibroblasts forming collagen
The end result of inflammation can be scarring. Here, scar tissue is predominantly composed of fibrous connective tissue made of collagen and is typically thicker, denser, and paler than surrounding tissues with absence of skin appendages.Scar tissue