GIT

Stomach

Objectives 1.Physiological anatomy 2.blood supply 3.innervation 4.Gastic secretion

Lec 4. 19 March 2013

Physiological Anatomy
Anatomically the stomach is divided into

Gastric Secretion

Oxyntic Glands -------HCL ,intrinsic factor,,pepsinogen, , and mucus. composed of three types cells : .

Basic mechanism of HCL Secretion

Basic steps for HCl formation

Q.explain why a slight increase in blood PH may occur following a heavy meal?. The elevated PH of blood ,especially in veins that carry blood away from the stomach ,is called “postprandial alkaline tide”


Stimulation of gastric acid secretion
Histamine: acetylcholine . Gastrin indirectly ---- ECL cells---Gastrin is the major regulator of the ECL cells. .

Phases of Gastric Secretion

Cephalic phase .

. Gastric Phase . Intestinal Phase

Q. What happens when Surgeon cuts the vagal nerve(parasympathetic cranial nerve) to the stomach