Carbohydrates

Galactose

GALACTOSE

GALACTOSE METABOLISM

GALACTOSE

Galactokinase

Galactose Galactose-1-phosphate
ATP ADP

Galactose-1-phosphate uridyl transferase

Galactose-1-p Glucose-1-p
+ UDP-glucose + UDP-galactose

GALACTOSE

UDP-galactose UDP-glucose

UMP

UDP-glucose glucose-1-p

glucose-6-p

Glucose-6-phosphatase
GLUCOSE

GALACTOSE

GALACTOSSEMIA:
This is a disease related to galactose metabolism.

Clinical manifestations include:

Prolonged neonatal jaundice
mental retardation
cataract





FRUCTOSE

FRUCTOSE

ATP Fructose
Fructokinase
ADP Fructose-1-p
Aldolase
Dihdroxyacetone + Glyceraldehyde
phosphate

GLYCOLYTIC PATHWAY

FRUCTOSE

ATP Glyceraldehyde-3-phosphate

ADP Glyceraldehyde

ATP
ADP
Glycerol
ATP ATP
ADP ADP
2-phosphoglycerate Glycerol-3-phosphate


Dihydroxyacetone phosphate

FRUCTOSE

Fructose intolerance:
Deficeincy of enzyme Fructose-1-phosphate ALDOLASE.

Clinical manifestations include:

Hypoglycemia
Vomitting
hepatomegaly