Practical Hematology
College Of Dentistry /Third Year
Dr.Zainab Ahmed Al-selevani
Normal Blood Cells morphology
Normal neutrophil in the center of the field. The red cells show normal hemoglobin.
Iron deficiency anaemia
Significant hypochromia and microcytosis is seen, as well as moderate variation in size and shape of the red cells.
Macrocytic Anaemia
An extremely large hypersegmented ( 8 lobes ) neutrophil, as are oval macrocytes.
B-thalassaemia major
Hypochromic microcytes, target cells, a nucleated red blood cell (normoblast ).
Sickle Cell Anaemia
A sickled cell is seen, as well as target cell in the center of the field. There is some anisocytosis and poikilocytosis.
Acute leukaemia ( blasts )
This smear shows:
Increased WBCs.
Blasts.
Reduced platelets
Blast cells characteristics
Relatively large.
High nuclear/cytoplasmic ratio.
Presence of nucleoli
Open chromatin
Chronic Lymphocytic Leukaemia ( CLL )
Increased WBCs
Absolute lymphocytosis.
Lymphocytes are mature looking with frequent torn cells (smear cells).
Chronic Myeloid Leukaemia ( CML )
Increased WBC count.
Granulocytes at different stages of maturation .
Basophilia.
