Subcutaneous Mycoses
Dr.Huda IbrahimSubcutaneous Mycoses
These are caused by fungi that grow in soil and on vegetation and are introduced into subcutaneous tissue through trauma.sporotrichosis
Sporothrix schenckii is a dimorphic fungus that live on vegetation. When introduced into the skin, typically by a thorn, it cause a local pustule or ulcer with nodules along the draining lymphatics .sporotrichosis
There is little systemic illness. Lesion may be chronic . * Sporotrichosis occure most often in gardeners, especially those who prune roses, because they may be stuck by a rose thorn.Cutaneous sporotrichosis Produces nodular lesions around the infection site Lymphocutaneous sporotrichosis Secondary lesions occur on the skin along the course of lymphatic vessels
sprotrichosis
Sporotrichosis ulcer.Lymphocutaneous sporotrichosis on the arm
Figure 22.20
sporotrichosis
In the clinical laboratory specimen, round or cigar-shaped budding yeasts are seen In culture, hyphae occur bearing oval conidia in clusters at the tip of slender conidiophores. The drug of choice for skin lesions is itraconazole.Chromoycosis
This is a slowly progressive granulomatous infection that is caused by several soil fungi (Fonsecaea, phialophora, cladosprium, etc) when introduced into the skin through the trauma. These fungi are collectively called dematiaceous fungi, so named because their conidia or hyphae are dark-colored, either gray or black.Chromoycosis
Wart like lesion with crusting abscesses extend along the lymphatics. The disease occure mainly in the tropics and is found on bare feet and legs. In the clinical laboratory, dark brown, round fungal cell are seen in leukocytes or giant cells.Chromoycosis
"Chromoblastomycosis, syn. chromomycosis; hyperkeratotic lesions foot; Fonsacaea (Phialophora) infection,In tissue these fungi form sclerotic bodies which are the reproductive forms dividing by fission. These organisms induce a granulomatous reaction. The disease is treated with oral flucytosine or thiabendazole, plus local surgery.
Figure 22.18
Mycetoma
Tumor like infections of skin, fascia, and bones of hands or feet Fungi are found in the soil Fungi introduced via wounds from contaminated twigs, thorns, or leaves Nodules form at site of infection that slowly worsen and spread Bone destruction can cause permanent deformity Surgical removal of the mycetoma is required for treatment