Hypertension
Globally, an estimated 26% of the world’s population (972 million people) has hypertension, and the prevalence is expected to increase to 29% by 2025, driven largely by increases in economically developing nations. Regarded as a primary contributor to heart disease and stroke, the first and third leading causes of death worldwide, respectively.Arterial Hypertension as a risk factor
Hypertension is a highly prevalent risk factor for cardiovascular disease Hypertension plays a major etiologic role in the development of cerebrovascular disease, ischemic heart disease, cardiac and renal failureLaboratory and instrumental investigation- routine tests
Serum total cholesterol, LDL, HDL Fasting serum triglycerides Fasting plasma glucose Serum potassium Serum uric acid Serum creatinine Haemoglobin and haematocrit Urinalysis Electrocardiogram EchocardiogramSecondary causes of AH
Renal parenchymal disease (most common cause)Renovascular hypertension (2nd most common cause)Pheochromocytoma Primary hyperaldosteronismCushing’s syndromeObstructive sleep apneaCoarctation of aortaDrug-induced hypertensionBenefits of Lowering BP
Average reductionStroke incidence 35–40% Myocardial infarction 20–25% Heart failure>50%Aim of antihypertensive therapy
The primary goal of treatment is to achieve (< 140/90 mm Hg) and treatment of all reversible risk factors are indicated In diabetes and in high risk patients BP target should be at least < 130/80 mmHgLifestyle changes
smoking cessation weight reduction reduction of alcohol intake physical exercise reduction of salt intake increase in fruit and vegetables intake decrease in saturated and total fat intake
Antihypertensive drugs
thiazide diuretics calcium antagonists (CA) ACE-inhibitors (ACEI) angiotensin receptor blockers (ARB) beta-blockers (BB)Dental Aspect
SBP< 140,DBP < 90 (I) Routine dental careSBP=140–159,DBP=90–99 (II) Recheck BP before starting routine dental careSBP=160–179,DBP=99–109 (III) Recheck BP and seek medical advice before routine dental care Restrict use of adrenaline/ epinephrine Conscious sedation may helpSBP> 180,DBP > 110 (IV) Recheck BP after 5 min quiet rest. Medical advice before dental care Only emergency care until BP controlled Avoid vasoconstrictors
An aspirating syringe should be used to give a LA, since epinephrine (adrenaline) in the anaesthetic given intravenously may (theoretically) increase hypertension and precipitate arrhythmias
Corticosteroids may raise the blood pressure and antihypertensive treatment may have to be adjusted accordingly. Some NSAIDs (indometacin, ibuprofen and naproxen) can reduce the efficacy of antihypertensive agents.
Antihypertensive drugs can sometimes cause orofacial side-effects, such as xerostomia, salivary gland swelling or pain, lichenoid reactions, erythema multiforme, angioedema, gingival swelling, sore mouth or paraesthesiae