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JABIR IBN HAYYAN MEDICAL UNIVERSITYCOLLEGE OF MEDICINE DEPARTMENT OF HUMAN ANATOMY

Histology of Female Reproductive System
Lecture By;
Dr. Hayder ALKifaee
6/4/2017

FEMALE REPRODUCTIVE SYSTEM

HISTOLOGY
Female reproductive system

Female Reproductive System Consists of

Paired ovaries
Uterine tubes
Uterus
Vagina
External Genitalia
Female reproductive system


Female Reproductive Organs

Female reproductive system




Female reproductive system

Cortex

Medulla

Female Reproductive Organs

Ovary
Almond shaped (3 x 1.5 x 1 cm)
Produce Oocytes
Produce Hormones
Female reproductive system





Female reproductive system

Coverings of Ovary

Female reproductive system

Coverings of Ovary

Female reproductive system

Menarche & Menopause

Menarche
Menopause period
Postmenopausal period

Follicular Growth & Development

Female reproductive system




Follicular Growth & Development
Beginning in Puberty with the release of FSH
Group of Primordial Follicles each month begins a process of follicular growth
Female reproductive system

Follicular Growth & Development

This involves Growth of the oocyte
Proliferation & changes in the Follicular cells
Proliferation & differentiation of the Stromal Fibroblasts
Female reproductive system

Primordial Follicle

Female reproductive system

Unilaminar Primary Follicle

Female reproductive system




Microvilli of Oocyte & Filopodia of Granluosa cells
Female reproductive system

Microvilli

Filopodia
Granluosa cell

Microvilli of Oocyte & Filopodia of Granluosa cells

Female reproductive system




Female reproductive system

Primordial Follicle

Unilaminar Follicle
Multilayered Follicle
Primary Follicle

Multilaminar Primary Follicle

Female reproductive system


Antral Follicle

Female reproductive system




Female reproductive system

Antrum

Granulosa
Theca interna & Externa
Antral Follicle
Preovulatory Follicle


Female reproductive system

Follicular Development

Graafian Follicle
Female reproductive system





Female reproductive system

Stages of Ovarian Follicle

Female reproductive system

Zona Pellucida

Granluosa Cell
Ultrastructure of Primary Follicle & Zona Pellucida

Follicular Fluid

Large GAG hyaluronic acid
Growth factors
Plasminogen
Fibrinogen
Anticoagulant heparan sulfate proteoglycan
High concentrations of steroids



Female reproductive system

Wall of Antral Follicle

Antrum
Granulosa
Theca I
Theca E
Stroma


Female reproductive system

Apoptosis of G. cells

Atresia of Follicle(Apoptosis & Autolysis)


Female reproductive system

Hormonal Regulation of Ovarian Function



Female reproductive system

Corpus Luteum (yellowish body)

Female reproductive system

Granlosa lutein cell

Theca lutein cell
Corpus LuteumGranulosa cells Granulosa lutein cells Theca interna cells Theca lutein cells


Female reproductive system


Remnants of corpus luteum are phagocytosed by macrophages, after which fibroblasts invade the area and produce a scar of dense connective tissue called a corpus albicans (L., white body).


Female reproductive system

Corpus Albicans (white body)



Female reproductive system

Uterine Tubes & Uterus

Female reproductive system

Uterine Tubes

Ampulla
Isthmus
infundibulum
Intramural

Wall of the Oviduct:

Mucosa
Muscularis
Serosa
Female reproductive system




Cross Section in Oviduct (Ampulla)
Female reproductive system




Female reproductive system

Mucosa of the Uterine Tube Wall

Female reproductive system

Ciliated Cell& Secretory (Peg Cell)

The Epithelium Cell Types:
Ciliated Cells in which ciliary movements sweep fluid toward the uterus
Secretory Peg Cells, nonciliated & often darker staining, often with an apical bulge into the lumen, which secrete glycoproteins of a nutritive mucus film that covers the epithelium


Female reproductive system



Ciliated Cell& Secretory (Peg Cell)

UTERUS Fundus, Body & Cervix

Female reproductive system

Uterine Wall Three Layers:

Perimetrium
Myometrium
Endometrium

Layers of Uterine Wall

Female reproductive system




Female reproductive system

Uterus


Female reproductive system

Correlation of Ovarian &Menstrual Cycle

Female reproductive system




Female reproductive system

Arterial Supply of Endometrium

Female reproductive system

proliferative

Secretory

Premenstrual

Proliferative, Secretory& Premenstrual phases



Female reproductive system

Cervix & Vagina

Cervix
Female reproductive system




Female reproductive system

Cervical canal

Simple columnar
Junction
Strat.squamous
Vagina
Exfoliative cytology of exocervix

Cervical mucosal glands


Transformation Zone(Squamo-Columnar Junction)
Female reproductive system




Female reproductive system

Epithelium

Muscular layer
Lamina propria
Vagina Mucosa, Muscular layer & Adventitia


Female reproductive system

External Genitalia (vulva)

Thank you



رفعت المحاضرة من قبل: Samih Al Hassan
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