
1
Fifth stage
Pediatric
Lec. 6
.د
رياض
1/3/2017
Kala azar
visceral leishmaniasis
• Parasitic infection endemic in Baghdad, India, Sudan, Africa. caused by many types of
leishmania well known one; L. donovani, transmitted by Sand fly. Clinical features
includes prolonged irregular fever hepatosplenomegaly,lymphadenopathy,
emaciation,
• Anemia, loss of weight, alopecia, infections due to neutropenia, bone marrow
invasion and suppression with thrombocytopenia. Diagnosis depend on serological
for antibodies like latex agglutination, followed by PCR.
• Definite diagnosis depends upon TEST TO SEE THE PARASITE IN THE BONE MARROW
ASPIRATE 65%. Also splenic needle aspirate give95% positive.
• Treatment is by IV sodium stiboguluconate(pentostam),for 3 weeks.