infection

Fifth stage

Pediatric
Lec. 6
د. رياض

1/3/2017

Kala azarvisceral leishmaniasis

Parasitic infection endemic in Baghdad, India, Sudan, Africa. caused by many types of leishmania well known one; L. donovani, transmitted by Sand fly. Clinical features includes prolonged irregular fever hepatosplenomegaly,lymphadenopathy, emaciation,
Anemia, loss of weight, alopecia, infections due to neutropenia, bone marrow invasion and suppression with thrombocytopenia. Diagnosis depend on serological for antibodies like latex agglutination, followed by PCR.
Definite diagnosis depends upon TEST TO SEE THE PARASITE IN THE BONE MARROW ASPIRATE 65%. Also splenic needle aspirate give95% positive.
Treatment is by IV sodium stiboguluconate(pentostam),for 3 weeks.