Syphilis
Definition: Syphilis is a systemic infection caused by the spirochete Treponema pallidium,which is transmitted mainly by direct sexual intercourse (venereal syphilis) and less commonly via placenta (congenital syphilis) or by accidental inoculation from the infectious Materials
T. Pallidum spirochetes cannot be cultured but are detected by silver stains, dark field examination and immunofluorescence technique