Blood Vessels pdf - نظري

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Lecture 1 - Atherosclerosis

Epidemiology of Atherosclerosis

Risk factors for atherosclerosis

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Pathogenesis (How do lesions develop?)

Many theories:-

Injury Theory

Oligoclclonality of Lesions

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Infection

Clinical manifestations of atherosclerosis

Morphology

1) Fatty Streak

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2) Atherosclerotic Plaque

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Lecture 2 - Aneurysms and Dissections

Abdominal Aortic Aneurysm

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Syphilitic Aneurysm

Aortic Dissection

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The risk and nature of serious complications of dissection depend strongly on the level of the
aorta affected. The most serious complications occur with dissections that involve the aorta
from the aortic valve to the arch.

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The classic clinical symptoms of aortic dissection are the sudden onset of pain, usually
beginning in the anterior chest, radiating to the back between the scapulae & moving downward
as the dissection progresses; the pain can be confused with that of myocardial infarction.

Types: two types

1) Type A dissections:-the more common proximal lesions, involving either the ascending aorta

called the DeBakey types I or DeBakey type II when involve both the ascending and
descending aorta.

2) Type B dissections distal lesions not involving the ascending part and usually beginning distal

to the subclavian artery (DeBakey type III).

Berry aneurysm