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Influenza A H1 N1

Dr Ghazi F ,Haji CARDIOLOGIST

Influenza Virus Types A and B

Type A(Seasonal, avian, swine influenza,….) Type B (Seasonal influenza)
Can cause significant disease
Generally causes milder disease but may also cause severe disease
Infects humans and other species (e.g., birds; H5N1)
Limited to humans
Can cause epidemics and pandemics (worldwide epidemics)
Generally causes milder epidemics
*

1920 1940 1960 1980 2000

H1N1
H2N2
H3N2
1918: “Spanish Flu” 1957: “Asian Flu” 1968: “Hong Kong Flu” 20-40 million deaths
1-4 million deaths
1-4 million deaths

The new virus must be efficiently transmitted from one human to another

Prerequisites for pandemic influenza
A new influenza virus emerges to which the general population has little/no immunity
The new virus must be able to replicate in humans and cause disease

The InfluenzaVirus

A H1N1 :new virus
The 2009 H1N1 virus is a hybrid of swine, avian and human strains Influenza A (H1N1)

Viral Re-assortment

Reassortment in pigs
Reassortment in humans
Pandemic Influenza Virus

Big droplets fall on people surfaces bed clothes

Courtesy of CDC

Signs and Symptoms

Human Influenza
Type of infection
Upper and lower respiratory
Fever
Yes
Headache
Yes
Cough
Yes
Respiratory symptoms
Varies; sore throat to difficulty breathing
Gastrointestinal symptoms
Uncommon, except children, elderly
Recovery
2-7 days

Swine flu


Cough etiquette
Respiratory etiquette Cover nose / mouth when coughing or sneezing Hand washing!

Voluntary Isolation

Separation and restricted movement of ill persons with contagious disease (often in a hospital setting and Primarily individual level) Isolate severe and mild cases Location of isolation (home, hospital) depends on several factors (severity of illness, the number of affected persons, the domestic setting) Do not wait for lab confirmation Plan for large number of severe cases Provide medical and social care

Patients Cared for at Home

Potential for transmissionMust educate family caregiversFever / symptom monitoringInfection control measuresHand washingUse of available material as mask …

Isolation Precautions

Source: Rosie Sokas, MD MOH UIL at Chicago
Droplet precautions: Surgical Masks

N-95 Filtering Masks

Personal Protective Equipment (PPE)

Antivirals- Oseltamivir

Treatment is 75 mg twice a day for 5 days. Prophylaxis is 75 mg once a day for 7 days after last exposure. Prophylaxis: High risk exposure (household contacts) Moderate risk (unprotected very close exposure to sick animals; HCW with unprotected exposure to patients) Low risk exposure: no need for prophylaxis unless activation of exceptional measures.

Thank you




رفعت المحاضرة من قبل: Mostafa Altae
المشاهدات: لقد قام 7 أعضاء و 116 زائراً بقراءة هذه المحاضرة








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