Glandular fever syndromes:
-These includes infectious mononucleosis, acute cytomegalovirus and acquired toxoplasmosis.
-The common features of these infections are:
1.Rarely spread between infected cases.
2.Most infections are subclinical.
3.Chronic infection may occur.
4.Activation of latent infection may occur.
5.Occasionally transmitted through blood or leucocyte transfusion.
6.Atypical lymphocyte  appear during acute infection.
7.Cytomegalovirus and toxoplasma can cause intrauterine infection and congenital disease.
******************
Gestational CMV infection:
-Most cases are subclinical.
-Suspension  arise by detection of heterophil antibody negative glandular fever in pregnancy.
-Congenital infection can occur at any stage of gestation.
-The risk of spread to the fetus is around 40%.
-The most important sequelae is the CNS involvement of the fetus.

*******************
Acquired cytomegalovirus infection:
@Clinical features:
-Hepatosplenomegaly .
-Lymphadenopathy,Pharangitis and tonsilitis are less
common.
-Jaundice is uncommon.
-Unusual complications include neurological involvement,
haemolytic anaemia, pericardtis, pneuonitis and
arthropathy.
@Investigations:
-Atypical lymphocytosis is not as prominent as in IM and
heterophil antibody test are negative.
-Liver function test are often abnormal with raised alkaline
phosphatase.
-Serological diagnosis (CMV specific IgM antibody ) .